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Altered Gut Microbiota Profiles in Sows and Neonatal Piglets
2018-09-01 · In conclusion, the present findings indicated that dysbiosis during active GAD manifested as alterations in gut bacterial community structure and composition. The gut microbiota may be a potential therapeutic and preventive target for patients with GAD. However, further studies using an appropriate design are required to test this hypothesis. The link between gut microbes and autism spectrum disorders (ASD) has been already observed in some studies, but some bacterial families/species were found to be inconsistently up or down regulated. This issue has been rarely explored in the Chinese population. In this study, we assessed whether or not gut microbiota dysbiosis was associated with children with ASD in China.
Schizophrenia (SZ) is a complex, chronic psychiatric disorder with a heterogeneous genetic and Materials and Methods. A total of 162 subjects were collected in this study from September 2017 to February While there’s still much to be learned, most scientists agree that an altered gut microbiome—specifically reduced microbial diversity and dysbiosis (microbial imbalance)—may play a role in a number of diseases, including IBS, IBD, obesity, diabetes, and cardiovascular disease. A study applying the enterotype concept found that diets high in protein and animal fat favored Bacteroides whereas diets high in carbohydrates favored Prevotella ( Wu et al., 2011 ). In mice, a high-fat, high-sugar diet has been shown to alter the composition of a humanized microbiota ( Turnbaugh et al., 2009b ). In the recent decade, gut microbiota has received growing interest due to its role in human health and disease. On the one hand, by utilizing the signaling pathways of the host and interacting with the immune system, the gut microbiota is able to maintain the homeostasis in human body. This important role is mainly modulated by the composition of microbiota, as a normal microbiota composition
Even among younger individuals, who are typically less likely to de-velop symptomatic COVID-19, patients with obesity or diabetes tend to manifest more The altered gut microbiota also promote inflammatory APCs, which in turn facilitate the expansion and activation of a number of different clonotypes of insulin-reactive CD8+ T cells, leading to the development of accelerated autoimmune diabetes in our NOD transgenic mouse model of autoimmune diabetes. 2020-06-01 · Altered nutrient status reprograms host inflammation and metabolic health via gut microbiota Author links open overlay panel Rachel M. Golonka a Xia Xiao b Ahmed A. Abokor a Bina Joe a Matam Vijay-Kumar a 2018-05-22 · Hypoxia induces senescence of bone marrow mesenchymal stem cells via altered gut microbiota.
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Our results show that bypass surgery led to fortification of the intestinal barrier functions, which may provide an explanation for the decreased risk of systemic endotoxemia in postoperative patients. 2018-09-01 · In conclusion, the present findings indicated that dysbiosis during active GAD manifested as alterations in gut bacterial community structure and composition.
Gut microbiota composition reflects disease severity and
Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome.
Contact. Print. Listen. PDF | Ulcerative colitis (UC) is characterized by chronic inflammation of the colonic mucosa. Administration of dextran sulfate sodium (DSS) to
av MJ Carranza-Naval · 2021 · Citerat av 1 — On the other hand, growing evidence has shown that alterations in the gut microbiota composition can alter normal brain function through the so-called
In conclusion, by applying two gene-modified mouse models, we showed that changes in sex steroid balance are linked to altered gut microbiota composition,
Sammanfattning : Altered gut microbiota configurations have been linked to human diseases.
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Results Pregnant women with IBD and their offspring presented with lower bacterial diversity and altered bacterial composition compared with control women and their babies. Maternal IBD was the main predictor of the microbiota diversity in the infant gut at 7, 14, 30, 60 and 90 days of life. Metabolic syndrome is a group of obesity-related metabolic abnormalities that increase an individual’s risk of developing type 2 diabetes and cardiovascular disease. Here, we show that mice genetically deficient in Toll-like receptor 5 (TLR5), a component of the innate immune system that is expressed in the gut mucosa and that helps defend against infection, exhibit hyperphagia and develop
We identified altered gut microbiota associated with disrupted plasma metabolite profiles in women with HIV. Two genera, Ruminococcus and Oscillospira, with fun We use cookies to enhance your experience on our website.By continuing to use our website, you are agreeing to our use of cookies.
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2021-03-01 · Using high-throughput sequencing technology, we observed that intratracheally instillated diesel PM 2.5 significantly altered the gut microbiota diversity and community. At the phylum and genus levels, principal coordinate analysis (PCoA) and principal component analysis (PCA) indicated pronounced segregation of microbiota compositions, which were further confirmed by β diversity analysis. ated with an altered gut microbiota that affects gut barrier integrity, such that patho-gens and pathobionts gain more access to the surface of the enterocytes (Fig. 1 and 2) (38, 39, 42–49). Even among younger individuals, who are typically less likely to de-velop symptomatic COVID-19, patients with obesity or diabetes tend to manifest more The altered gut microbiota also promote inflammatory APCs, which in turn facilitate the expansion and activation of a number of different clonotypes of insulin-reactive CD8+ T cells, leading to the development of accelerated autoimmune diabetes in our NOD transgenic mouse model of autoimmune diabetes.